Hs05307488_cn

• Gene Symbol: ALOX5AP
• Assay Reference Genome Location: Chr.13:30716109 on build GRCh38
• Cytoband: 13q12.3

Target Gene Details

• Entrez Gene ID: 241
• Gene Name: arachidonate 5-lipoxygenase activating protein
• Gene Aliases: FLAP
• Location: Chr.13:30713478-30764428 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALOX5AP	NM_001204406.1			NP_001191335.1
	AK314143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832574	Chr.13:30657196 - 30822408 on Build GRCh38	Gain	LINC00398 USPL1 ALOX5AP
esv3406702	Chr.13:30716015 - 30717613 on Build GRCh38	Duplication	ALOX5AP

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transferase

Gene Ontology Categories:

Process(es)

leukotriene metabolic process
leukotriene biosynthetic process
lipoxygenase pathway
positive regulation of catalytic activity
protein homotrimerization
cellular response to calcium ion
lipoxin metabolic process

Function(s)

glutathione transferase activity
leukotriene-C4 synthase activity
glutathione peroxidase activity
protein binding
enzyme activator activity
protein N-terminus binding
arachidonic acid binding