Hs03540249_cn

• Gene Symbol: SLC9B1
• Assay Reference Genome Location: Chr.4:103018689 on build GRCh38
• Cytoband: 4q24

Target Gene Details

• Entrez Gene ID: 150159
• Gene Name: solute carrier family 9 member B1
• Gene Aliases: NHA1, NHEDC1
• Location: Chr.4:102885048-103019739 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC9B1	NM_001100874.2			NP_001094344.1
	NM_139173.3			NP_631912.2
	NR_047513.1
	NR_047515.1
	XM_006714093.3			XP_006714156.1
	XM_011531622.1			XP_011529924.1
	AF447585.1			AAM22868.1
	AK313592.1
	AY461581.1
	BC110794.1			AAI10795.1
	BC132712.1
	BC136966.1
	DQ003059.1			AAY21808.1

Target Gene Details

• Entrez Gene ID: 133308
• Gene Name: solute carrier family 9 member B2
• Gene Aliases: NHA2, NHE10, NHEDC2
• Location: Chr.4:103018033-103077371 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC9B2	XM_006714085.2	13	3948	XP_006714148.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv4445	Chr.4:103003411 - 103034963 on Build GRCh38	Insertion	SLC9B2 SLC9B1
nsv461598	Chr.4:102886563 - 103032232 on Build GRCh38	Loss	SLC9B2 CISD2 SLC9B1
nsv830021	Chr.4:103013297 - 103179431 on Build GRCh38	Loss	SLC9B2 BDH2 SLC9B1 CENPE
esv2759270	Chr.4:102859548 - 103136164 on Build GRCh38	Gain	UBE2D3 SLC9B2 CISD2 BDH2 SLC9B1 CENPE

More Information

Additional Information:

For this assay, SNP(s) [rs79723528] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

ion transmembrane transport
sodium ion transmembrane transport
hydrogen ion transmembrane transport
sodium ion transport
positive regulation of osteoclast development

Function(s)

sodium:proton antiporter activity
monovalent cation:proton antiporter activity