Hs02895300_cn

• Gene Symbol: ST20
• Assay Reference Genome Location: Chr.15:79922777 on build GRCh38
• Cytoband: 15q25.1

Target Gene Details

• Entrez Gene ID: 400410
• Gene Name: suppressor of tumorigenicity 20
• Gene Aliases: HCCS-1
• Location: Chr.15:79898840-79923754 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ST20	NM_001100880.2			NP_001094350.1
	NM_001199757.1			NP_001186686.1
	NR_037652.1
	NR_037653.1
	AA282293.1
	AF249277.1			AAG17280.1
	BM559302.1
	BQ680929.1

Target Gene Details

• Entrez Gene ID: 283687
• Gene Name: ST20 antisense RNA 1
• Gene Aliases: C15orf37
• Location: Chr.15:79922771-79924854 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ST20-AS1	NR_028330.1
	AK091107.1			BAC03584.1
	BC101201.1			AAI01202.1
	BC101202.1			AAI01203.1
	BC101203.1			AAI01204.1

Target Gene Details

• Entrez Gene ID: 100528021
• Gene Name: ST20-MTHFS readthrough
• Gene Aliases: -
• Location: Chr.15:79843547-79923106 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ST20-MTHFS	NM_001199760.1			NP_001186689.1
	BG705061.1
	CK002935.1
	DB495490.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833066	Chr.15:79878078 - 80033241 on Build GRCh38	Loss	ST20-AS1 ST20 ST20-MTHFS MTHFS BCL2A1
dgv155n21	Chr.15:79919071 - 79923673 on Build GRCh38	Loss	ST20-AS1 ST20 ST20-MTHFS
esv3637009	Chr.15:79898247 - 79960449 on Build GRCh38	Loss	ST20-AS1 ST20 ST20-MTHFS
nsv833065	Chr.15:79760661 - 79982480 on Build GRCh38	Loss	ST20-AS1 ST20 ST20-MTHFS MTHFS BCL2A1
esv2660680	Chr.15:79898180 - 79960294 on Build GRCh38	Deletion	ST20-AS1 ST20 ST20-MTHFS
esv3581779	Chr.15:79902138 - 79936035 on Build GRCh38	Loss	ST20-AS1 ST20 ST20-MTHFS

More Information

Additional Information:

For this assay, SNP(s) [rs77136548] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

release of cytochrome c from mitochondria
mitochondrial fusion
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of apoptotic process
transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

channel activity
protein homodimerization activity
protein heterodimerization activity