Hs02714699_cn

• Gene Symbol: CYP7B1
• Assay Reference Genome Location: Chr.8:64616012 on build GRCh38
• Cytoband: 8q12.3

Target Gene Details

• Entrez Gene ID: 9420
• Gene Name: cytochrome P450 family 7 subfamily B member 1
• Gene Aliases: CBAS3, CP7B, SPG5A
• Location: Chr.8:64590851-64798791 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP7B1	NM_001324112.1	3	733	NP_001311041.1
	NM_004820.4	3	733	NP_004811.1
	XM_017014002.1	4	19131	XP_016869491.1
	AF029403.1	3	663	AAC95426.1
	AF127090.1	3	688	AAD20021.1
	BC029155.1	3	660
	BC136574.1	3	703

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv611449	Chr.8:64598475 - 64630844 on Build GRCh38	Loss	CYP7B1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

bile acid biosynthetic process
cholesterol metabolic process
sterol metabolic process
negative regulation of intracellular estrogen receptor signaling pathway
B cell chemotaxis
positive regulation of epithelial cell proliferation
oxidation-reduction process
prostate gland epithelium morphogenesis

Function(s)

iron ion binding
oxysterol 7-alpha-hydroxylase activity
heme binding
25-hydroxycholesterol 7alpha-hydroxylase activity