Hs02430218_cn

• Gene Symbol: ADCY8
• Assay Reference Genome Location: Chr.8:130780664 on build GRCh38
• Cytoband: 8q24.22

Target Gene Details

• Entrez Gene ID: 114
• Gene Name: adenylate cyclase 8
• Gene Aliases: AC8, ADCY3, HBAC1
• Location: Chr.8:130780300-131041604 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADCY8	NM_001115.2	18	3738	NP_001106.1
	XM_005250769.3	17	3771	XP_005250826.1
	XM_006716501.3	17	3867	XP_006716564.1
	XM_017013006.1	16	3539	XP_016868495.1
	DQ104739.1	15	3089
	GQ472223.1	18	5576
	M83533.1	12	1754	AAA35523.2
	Z35309.1	18	5576	CAA84552.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1016494	Chr.8:130133708 - 131222639 on Build GRCh38	Gain	ASAP1-IT1 ADCY8 ASAP1
nsv612294	Chr.8:130632833 - 130911131 on Build GRCh38	Gain	ADCY8
nsv831462	Chr.8:130691873 - 130883547 on Build GRCh38	Gain	ADCY8

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

renal water homeostasis
cAMP biosynthetic process
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
learning or memory
long-term memory
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus

Function(s)

adenylate cyclase activity
ATP binding
calcium- and calmodulin-responsive adenylate cyclase activity
metal ion binding