Hs02378806_cn

• Gene Symbol: SDS
• Assay Reference Genome Location: Chr.12:113392986 on build GRCh38
• Cytoband: 12q24.13

Target Gene Details

• Entrez Gene ID: 10993
• Gene Name: serine dehydratase
• Gene Aliases: SDH
• Location: Chr.12:113392445-113403887 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SDS	NM_006843.2	8	1064	NP_006834.2
	AK124290.1	1	1254
	AK292760.1	8	1060
	BG566257.1	3	391
	BU740747.1	1	557
	J05037.1	8	1031	AAA36604.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv519540	Chr.12:113042705 - 113459599 on Build GRCh38	Gain+Loss	SDS DDX54 SLC8B1 RASAL1 RITA1 DTX1 MIR7106 MIR6762 PLBD2 TPCN1 CFAP73 SDSL IQCD
esv3892265	Chr.12:113099321 - 113527932 on Build GRCh38	Gain	SDS DDX54 SLC8B1 RASAL1 LHX5-AS1 RITA1 LHX5 MIR7106 MIR6762 PLBD2 TPCN1 CFAP73 SDSL IQCD
esv3630792	Chr.12:112988703 - 113838810 on Build GRCh38	Gain	SDS DDX54 SLC8B1 RASAL1 LHX5-AS1 RITA1 LHX5 DTX1 MIR7106 MIR6762 PLBD2 TPCN1 OAS2 CFAP73 LINC01234 SDSL IQCD RBM19

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydratase

Gene Ontology Categories:

Process(es)

gluconeogenesis
L-serine catabolic process
pyruvate biosynthetic process

Function(s)

L-serine ammonia-lyase activity
L-threonine ammonia-lyase activity
pyridoxal phosphate binding
protein homodimerization activity