Hs01728610_cn

• Gene Symbol: CYP7A1
• Assay Reference Genome Location: Chr.8:58497180 on build GRCh38
• Cytoband: 8q12.1

Target Gene Details

• Entrez Gene ID: 1581
• Gene Name: cytochrome P450 family 7 subfamily A member 1
• Gene Aliases: CP7A, CYP7, CYPVII
• Location: Chr.8:58490178-58500161 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP7A1	NM_000780.3			NP_000771.2
	BC101777.1			AAI01778.1
	BC112184.1			AAI12185.1
	M93133.1			AAA58435.1
	X56088.1			CAA39568.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv994118	Chr.8:58489845 - 58497470 on Build GRCh38	Deletion	CYP7A1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

bile acid biosynthetic process
cholesterol catabolic process
sterol metabolic process
cholesterol homeostasis
oxidation-reduction process
regulation of bile acid biosynthetic process
cellular response to glucose stimulus
cellular response to cholesterol

Function(s)

iron ion binding
cholesterol 7-alpha-monooxygenase activity
heme binding