Hs01641327_cn

• Gene Symbol: CH25H
• Assay Reference Genome Location: Chr.10:89206693 on build GRCh38
• Cytoband: 10q23.31

Target Gene Details

• Entrez Gene ID: 9023
• Gene Name: cholesterol 25-hydroxylase
• Gene Aliases: C25H
• Location: Chr.10:89205937-89207314 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CH25H	NM_003956.3	1	622	NP_003947.1
	AF059214.1	1	610	AAC97483.1
	AK314865.1	1	627
	BC017843.1	1	622	AAH17843.1
	BC072430.1	1	602	AAH72430.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831944	Chr.10:89062897 - 89207261 on Build GRCh38	Gain	MIR4679-2 CH25H MIR4679-1
nsv517170	Chr.10:89171845 - 89215450 on Build GRCh38	Loss	LIPA CH25H
nsv551858	Chr.10:89180930 - 89215450 on Build GRCh38	Loss	LIPA CH25H
dgv951n100	Chr.10:89202275 - 89219336 on Build GRCh38	Loss	LIPA CH25H
nsv1038123	Chr.10:89194660 - 89232372 on Build GRCh38	Loss	LIPA CH25H
nsv437127	Chr.10:89180246 - 89208346 on Build GRCh38	Loss	CH25H
esv2759775	Chr.10:89075307 - 89257729 on Build GRCh38	Loss	LIPA CH25H

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

lipid metabolic process
fatty acid biosynthetic process
bile acid biosynthetic process
cholesterol metabolic process
sterol biosynthetic process
B cell chemotaxis
oxidation-reduction process

Function(s)

cholesterol 25-hydroxylase activity
iron ion binding
steroid hydroxylase activity