Hs01624670_cn

• Gene Symbol: CYP1A2
• Assay Reference Genome Location: Chr.15:74748859 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1544
• Gene Name: cytochrome P450 family 1 subfamily A member 2
• Gene Aliases: CP12, P3-450, P450(PA)
• Location: Chr.15:74748843-74756600 on Build GRCh38
• Assay Gene Location: Overlaps - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A2	NM_000761.4			NP_000752.2
	BC067424.1			AAH67424.1
	BC067425.1			AAH67425.1
	BC067426.1			AAH67426.1
	BC067427.1			AAH67427.1
	BC067428.1			AAH67428.1
	BC067429.1			AAH67429.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	EDC3 ULK3 MIR4513 CYP1A2 CYP1A1 SCAMP2 CPLX3 LMAN1L MIR6882 CSK
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC101929333 REC114 ULK3 STRA6 CPLX3 C15orf59 RPP25 ADPGK CLK3 ISLR2 SEMA7A MIR6882 STOML1 NEO1 CSK LOC105376731 GOLGA6A LOC729739 LOC107984728 MIR6881 CYP11A1 PML CD276 UBL7-AS1 LOC102723750 FAM219B NPTN-IT1 LOXL1-AS1 HIGD2B TBC1D21 LOC283731 ISLR SCAMP5 CYP1A1 SCAMP2 LOC732265 MPI C15orf39 BBS4 C15orf59-AS1 ADPGK-AS1 ARID3B COX5A LMAN1L CCDC33 EDC3 MIR4513 NPTN CYP1A2 UBL7 HCN4 PPCDC LOXL1 GOLGA6C

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

steroid catabolic process
porphyrin-containing compound metabolic process
xenobiotic metabolic process
toxin biosynthetic process
post-embryonic development
alkaloid metabolic process
regulation of gene expression
monoterpenoid metabolic process
drug metabolic process
dibenzo-p-dioxin metabolic process
epoxygenase P450 pathway
lung development
methylation
response to estradiol
response to lipopolysaccharide
monocarboxylic acid metabolic process
response to immobilization stress
drug catabolic process
exogenous drug catabolic process
cellular respiration
heterocycle metabolic process
hydrogen peroxide biosynthetic process
oxidation-reduction process
oxidative demethylation
cellular response to cadmium ion
oxidative deethylation
omega-hydroxylase P450 pathway

Function(s)

monooxygenase activity
iron ion binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
enzyme binding
heme binding
demethylase activity
caffeine oxidase activity
aromatase activity