Hs06344527_cn

• Gene Symbol: TPH2
• Assay Reference Genome Location: Chr.12:71942802 on build GRCh38
• Cytoband: 12q21.1

Target Gene Details

• Entrez Gene ID: 121278
• Gene Name: tryptophan hydroxylase 2
• Gene Aliases: ADHD7, NTPH
• Location: Chr.12:71938846-72032441 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPH2	NM_173353.3			NP_775489.2
	AK094614.1			BAC04385.1
	AY098914.1			AAM28946.1
	BC114442.1
	BC114499.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518498	Chr.12:71913836 - 72114999 on Build GRCh38	Loss	TBC1D15 TRHDE TPH2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

circadian rhythm
aromatic amino acid family metabolic process
response to activity
response to nutrient levels
serotonin biosynthetic process
response to estrogen
indolalkylamine biosynthetic process
response to glucocorticoid
response to calcium ion
oxidation-reduction process
cellular response to lithium ion

Function(s)

tryptophan 5-monooxygenase activity
iron ion binding
amino acid binding