Hs05719943_cn

• Gene Symbol: KMO
• Assay Reference Genome Location: Chr.1:241544054 on build GRCh38
• Cytoband: 1q43

Target Gene Details

• Entrez Gene ID: 8564
• Gene Name: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
• Gene Aliases: dJ317G22.1
• Location: Chr.1:241531883-241595647 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KMO	NM_003679.4			NP_003670.2
	XM_005273337.1			XP_005273394.1
	XM_005273338.3			XP_005273395.1
	XM_017002649.1			XP_016858138.1
	AF056032.1			AAC62615.1
	AK291558.1
	AK310937.1
	AU137977.1
	BC005297.1			AAH05297.1
	BP276365.1
	Y13153.1			CAA73613.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv525983	Chr.1:241543233 - 241548401 on Build GRCh38	Loss	KMO
nsv549460	Chr.1:241331278 - 241669985 on Build GRCh38	Gain	CHML RGS7 WDR64 KMO OPN3 FH
nsv1002214	Chr.1:241295639 - 241936488 on Build GRCh38	Gain	CHML EXO1 RGS7 WDR64 KMO OPN3 FH

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

tryptophan catabolic process
response to salt stress
tryptophan catabolic process to kynurenine
NAD metabolic process
quinolinate biosynthetic process
'de novo' NAD biosynthetic process from tryptophan
anthranilate metabolic process
secondary metabolite biosynthetic process
oxidation-reduction process
kynurenine metabolic process

Function(s)

kynurenine 3-monooxygenase activity
NAD(P)H oxidase activity
flavin adenine dinucleotide binding
FAD binding