Hs05381069_cn

• Gene Symbol: CYP1A2
• Assay Reference Genome Location: Chr.15:74749321 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1544
• Gene Name: cytochrome P450 family 1 subfamily A member 2
• Gene Aliases: CP12, P3-450, P450(PA)
• Location: Chr.15:74748843-74756600 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A2	NM_000761.4			NP_000752.2
	BC067424.1			AAH67424.1
	BC067425.1			AAH67425.1
	BC067426.1			AAH67426.1
	BC067427.1			AAH67427.1
	BC067428.1			AAH67428.1
	BC067429.1			AAH67429.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	CPLX3 ULK3 MIR6882 SCAMP2 CYP1A2 CSK EDC3 CYP1A1 MIR4513 LMAN1L
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	LOC283731 STRA6 ISLR SCAMP5 LOC729739 PPCDC MIR6881 LOXL1-AS1 MIR6882 NPTN C15orf59-AS1 HIGD2B ARID3B ULK3 CYP1A2 PML CCDC33 LOC107984728 COX5A CLK3 ISLR2 CYP11A1 FAM219B LOC732265 RPP25 ADPGK UBL7 LOC101929333 NEO1 NPTN-IT1 LMAN1L STOML1 ADPGK-AS1 CPLX3 CSK EDC3 CYP1A1 MPI UBL7-AS1 CD276 LOXL1 HCN4 REC114 GOLGA6C MIR4513 TBC1D21 BBS4 SCAMP2 C15orf59 GOLGA6A SEMA7A LOC102723750 LOC105376731 C15orf39

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

steroid catabolic process
porphyrin-containing compound metabolic process
xenobiotic metabolic process
toxin biosynthetic process
post-embryonic development
alkaloid metabolic process
regulation of gene expression
monoterpenoid metabolic process
drug metabolic process
dibenzo-p-dioxin metabolic process
epoxygenase P450 pathway
lung development
methylation
response to estradiol
response to lipopolysaccharide
monocarboxylic acid metabolic process
response to immobilization stress
drug catabolic process
exogenous drug catabolic process
cellular respiration
heterocycle metabolic process
hydrogen peroxide biosynthetic process
oxidation-reduction process
oxidative demethylation
cellular response to cadmium ion
oxidative deethylation
omega-hydroxylase P450 pathway

Function(s)

monooxygenase activity
iron ion binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
enzyme binding
heme binding
demethylase activity
caffeine oxidase activity
aromatase activity