Hs05220025_cn

• Gene Symbol: CYP2C8
• Assay Reference Genome Location: Chr.10:95047524 on build GRCh38
• Cytoband: 10q23.33

Target Gene Details

• Entrez Gene ID: 1558
• Gene Name: cytochrome P450 family 2 subfamily C member 8
• Gene Aliases: CPC8, CYPIIC8, MP-12/MP-20
• Location: Chr.10:95036772-95069512 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP2C8	NM_000770.3			NP_000761.3
	NM_001198853.1			NP_001185782.1
	NM_001198854.1			NP_001185783.1
	NM_001198855.1			NP_001185784.1
	AK292753.1
	AK293327.1
	AK293328.1
	AK298401.1
	AK303813.1
	AK315823.1
	BC020596.1			AAH20596.1
	CD014119.1
	M17397.1			AAA35739.1
	M17398.1			AAA35740.1
	M21941.1			AAA52160.1
	M21942.1			AAA52161.1
	Y00498.1			CAA68550.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv551964	Chr.10:95045614 - 95102529 on Build GRCh38	Loss	CYP2C8
esv3624264	Chr.10:94923968 - 95099386 on Build GRCh38	Gain	CYP2C9 CYP2C8
nsv1035409	Chr.10:94735420 - 95072300 on Build GRCh38	Loss	CYP2C9 CYP2C8 CYP2C19 CYP2C18
nsv1044182	Chr.10:95024239 - 95054932 on Build GRCh38	Gain	CYP2C8
nsv1050544	Chr.10:95007177 - 95054932 on Build GRCh38	Gain	CYP2C8
esv2761618	Chr.10:95024251 - 95054932 on Build GRCh38	Gain	CYP2C8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, oxygenase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

organic acid metabolic process
xenobiotic metabolic process
drug metabolic process
epoxygenase P450 pathway
exogenous drug catabolic process
oxidation-reduction process
oxidative demethylation
omega-hydroxylase P450 pathway

Function(s)

monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
oxygen binding
heme binding
caffeine oxidase activity
aromatase activity