Hs04621624_cn

• Gene Symbol: MLK7-AS1
• Assay Reference Genome Location: Chr.2:173210794 on build GRCh38
• Cytoband: 2q31.1

Target Gene Details

• Entrez Gene ID: 339751
• Gene Name: MLK7 antisense RNA 1
• Gene Aliases: -
• Location: Chr.2:173197712-173282036 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MLK7-AS1	NR_033882.1

Target Gene Details

• Entrez Gene ID: 51776
• Gene Name: sterile alpha motif and leucine zipper containing kinase AZK
• Gene Aliases: AZK, MLK7, MLT, MLTK, MRK, SFMMP, mlklak, pk
• Location: Chr.2:173075435-173268009 on Build GRCh38
• Assay Gene Location: Within Intron 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZAK	NM_016653.2			NP_057737.2
	NM_133646.2			NP_598407.1
	XM_005246640.2			XP_005246697.1
	XM_017004323.1			XP_016859812.1
	XM_017004324.1			XP_016859813.1
	AB030034.1			BAB12040.1
	AB041883.1
	AB049733.1			BAB16444.1
	AB049734.1			BAB16445.1
	AB208974.1			BAD92211.1
	AF238255.1			AAF63490.1
	AF251441.1			AAF65822.1
	AF325454.1			AAK11615.1
	AF465843.1	10	1979	AAO33376.1
	AF480461.1			AAL85891.1
	AF480462.1			AAL85892.1
	AK056310.1
	AK291825.1
	AK298634.1
	AL833180.1
	BC001401.2			AAH01401.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3037	Chr.2:173190146 - 173223386 on Build GRCh38	Insertion	ZAK MLK7-AS1
nsv834460	Chr.2:173054736 - 173220560 on Build GRCh38	Gain	ZAK MLK7-AS1
esv3584178	Chr.2:173210824 - 173224533 on Build GRCh38	Loss	ZAK MLK7-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs77447718] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

cell cycle checkpoint
DNA damage checkpoint
activation of MAPKK activity
protein phosphorylation
response to stress
cytoskeleton organization
cell cycle arrest
activation of JUN kinase activity
cell death
cell proliferation
response to radiation
cell differentiation
intracellular signal transduction
embryonic digit morphogenesis
positive regulation of apoptotic process
limb development

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
poly(A) RNA binding