Hs03550766_cn

• Gene Symbol: NPR3
• Assay Reference Genome Location: Chr.5:32708995 on build GRCh38
• Cytoband: 5p13.3

Target Gene Details

• Entrez Gene ID: 4883
• Gene Name: natriuretic peptide receptor 3
• Gene Aliases: ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC
• Location: Chr.5:32689076-32791724 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NPR3	XM_011514047.1			XP_011512349.1
	XM_011514048.2			XP_011512350.1
	XM_011514049.2			XP_011512351.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1017141	Chr.5:32615443 - 32722393 on Build GRCh38	Gain	NPR3
esv3604616	Chr.5:32625459 - 32725468 on Build GRCh38	Gain	NPR3
esv2759338	Chr.5:32245255 - 32738538 on Build GRCh38	Loss	ZFR NPR3 MTMR12 SUB1 MIR579

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

skeletal system development
osteoclast proliferation
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
regulation of blood pressure
cyclic nucleotide biosynthetic process
cAMP-mediated signaling
pancreatic juice secretion
regulation of osteoblast proliferation
positive regulation of urine volume
phosphatidylinositol-mediated signaling
negative regulation of smooth muscle cell proliferation
positive regulation of nitric-oxide synthase activity

Function(s)

adenylate cyclase activity
G-protein coupled peptide receptor activity
natriuretic peptide receptor activity
peptide hormone binding
hormone binding
protein homodimerization activity