Hs02156789_cn

• Gene Symbol: CYP24A1
• Assay Reference Genome Location: Chr.20:54154654 on build GRCh38
• Cytoband: 20q13.2

Target Gene Details

• Entrez Gene ID: 1591
• Gene Name: cytochrome P450 family 24 subfamily A member 1
• Gene Aliases: CP24, CYP24, HCAI, HCINF1, P450-CC24
• Location: Chr.20:54145731-54173985 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP24A1	NM_000782.4	12	2061	NP_000773.2
	NM_001128915.1	11	1863	NP_001122387.1
	XM_005260304.4	12	2241	XP_005260361.1
	XM_017027691.1	12	2089	XP_016883180.1
	XM_017027692.1			XP_016883181.1
	XM_017027693.1	11	2043	XP_016883182.1
	BC109083.1	11	1550	AAI09084.1
	BC109084.1	11	1550	AAI09085.1
	L13286.1	12	2053	AAA62379.1
	N29030.1	1	54

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv586224	Chr.20:53858311 - 54662951 on Build GRCh38	Gain	CYP24A1 MIR4756 SUMO1P1 BCAS1 DOK5 PFDN4
nsv1058882	Chr.20:54149440 - 54177833 on Build GRCh38	Loss	CYP24A1
nsv834010	Chr.20:54143285 - 54316400 on Build GRCh38	Loss	CYP24A1 PFDN4
nsv1063981	Chr.20:54148778 - 54160074 on Build GRCh38	Loss	CYP24A1
nsv586281	Chr.20:54148810 - 54154632 on Build GRCh38	Loss	CYP24A1
esv2762085	Chr.20:54148790 - 54160086 on Build GRCh38	Loss	CYP24A1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

osteoblast differentiation
vitamin metabolic process
response to vitamin D
vitamin D metabolic process
vitamin D catabolic process
oxidation-reduction process
vitamin D receptor signaling pathway

Function(s)

iron ion binding
25-hydroxycholecalciferol-24-hydroxylase activity
oxidoreductase activity
heme binding
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity