Hs01719928_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137306917 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 32

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AI682614.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TUBB4B STPG3 CYSRT1 EXD3 ANAPC2 SLC34A3 C9orf173-AS1 RNF208 TMEM203 FAM166A RNF224 NRARP NELFB TOR4A SSNA1 NDOR1 TPRN
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	NELFB TUBB4B TOR4A STPG3 CYSRT1 EXD3 SLC34A3 C9orf173-AS1 FAM166A RNF224 NRARP
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 EXD3 ENTPD8
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	PRR31 C9orf172 FBXW5 DPP7 PTGDS LCN12 ANAPC2 MAN1B1-AS1 FUT7 RNF208 GRIN1 RABL6 TMEM210 TUBB4B STPG3 PHPT1 MIR4479 C9orf173-AS1 MIR3621 NELFB LCNL1 C8G NDOR1 NSMF TPRN ENTPD2 UAP1L1 CCDC183-AS1 SLC34A3 CCDC183 MIR7114 TMEM203 NPDC1 LOC101930307 FAM166A MAMDC4 TOR4A C9orf139 SAPCD2 C9orf142 CYSRT1 EXD3 ENTPD8 RNF224 NRARP PNPLA7 ABCA2 CLIC3 TRAF2 SSNA1 NOXA1 LRRC26 MIR4292 EDF1 MAN1B1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TMEM210 TUBB4B STPG3 CYSRT1 EXD3 ANAPC2 SLC34A3 C9orf173-AS1 RNF208 TMEM203 FAM166A RNF224 NRARP MIR3621 NELFB GRIN1 TOR4A SSNA1 NDOR1 LRRC26 TPRN
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TMEM210 TUBB4B STPG3 CYSRT1 EXD3 ANAPC2 SLC34A3 C9orf173-AS1 RNF208 TMEM203 ENTPD8 FAM166A RNF224 NRARP MIR3621 NELFB GRIN1 TOR4A SSNA1 NOXA1 NDOR1 LRRC26 TPRN
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	TOR4A EXD3 NRARP
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	PRR31 LOC100128593 C9orf172 FBXW5 DPP7 PTGDS LCN12 ANAPC2 MAN1B1-AS1 FUT7 RNF208 GRIN1 SNORA17B FAM69B RABL6 TMEM210 TUBB4B LCN6 STPG3 PHPT1 MIR4479 C9orf173-AS1 MIR3621 HSPC324 NELFB LCNL1 C8G NDOR1 MIR126 TPRN ENTPD2 UAP1L1 CCDC183-AS1 SLC34A3 CCDC183 TMEM203 NPDC1 LOC101930307 FAM166A MAMDC4 TOR4A LINC01451 C9orf139 SAPCD2 SNHG7 SNORA17A C9orf142 LCN15 LCN10 TMEM141 MIR6722 CYSRT1 EXD3 RNF224 NRARP EGFL7 AGPAT2 ABCA2 CLIC3 TRAF2 SSNA1 LRRC26 MIR4292 LCN8 EDF1 MAN1B1

More Information

Additional Information:

For this assay, SNP(s) [rs113731401] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding