Hs01671076_cn

• Gene Symbol: ALKBH1
• Assay Reference Genome Location: Chr.14:77675666 on build GRCh38
• Cytoband: 14q24.3

Target Gene Details

• Entrez Gene ID: 8846
• Gene Name: alkB homolog 1, histone H2A dioxygenase
• Gene Aliases: ABH, ABH1, ALKBH, alkB, hABH
• Location: Chr.14:77672404-77708038 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALKBH1	NM_006020.2			NP_006011.2
	BC015024.1			AAH15024.1
	BC025787.1			AAH25787.1
	X91992.1			CAA63047.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3635010	Chr.14:77630281 - 77745656 on Build GRCh38	Gain	ALKBH1 SLIRP SNW1
esv34940	Chr.14:77638554 - 77756455 on Build GRCh38	Gain	ALKBH1 SLIRP SNW1
nsv1053810	Chr.14:77521528 - 77681977 on Build GRCh38	Gain	ALKBH1 SPTLC2
esv3635012	Chr.14:77644082 - 77697186 on Build GRCh38	Gain	ALKBH1
nsv521287	Chr.14:77641660 - 77744882 on Build GRCh38	Gain	ALKBH1 SLIRP SNW1
esv2759998	Chr.14:77607837 - 77796229 on Build GRCh38	Gain	ALKBH1 SLIRP SPTLC2 C14orf178 SNW1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

in utero embryonic development
neuron migration
placenta development
DNA repair
DNA dealkylation involved in DNA repair
regulation of gene expression
neuron projection development
RNA repair
negative regulation of neuron apoptotic process
developmental growth
positive chemotaxis
oxidative demethylation
DNA demethylation

Function(s)

DNA-(apurinic or apyrimidinic site) lyase activity
ferrous iron binding
chemoattractant activity
methylcytosine dioxygenase activity