Hs00954627_cn

• Gene Symbol: TPH1
• Assay Reference Genome Location: Chr.11:18021031 on build GRCh38
• Cytoband: 11p15.1

Target Gene Details

• Entrez Gene ID: 7166
• Gene Name: tryptophan hydroxylase 1
• Gene Aliases: TPRH, TRPH
• Location: Chr.11:18020537-18040788 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPH1	NM_004179.2	10	1321	NP_004170.1
	AY196346.1			AAO72076.1
	BC106739.1			AAI06740.1
	BC106740.2
	BM451912.1	3	317
	X52836.1			CAA37018.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832079	Chr.11:17906420 - 18026196 on Build GRCh38	Loss	TPH1 SERGEF

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

circadian rhythm
aromatic amino acid family metabolic process
negative regulation of ossification
response to immobilization stress
serotonin biosynthetic process
positive regulation of fat cell differentiation
indolalkylamine biosynthetic process
bone remodeling
oxidation-reduction process
mammary gland alveolus development

Function(s)

tryptophan 5-monooxygenase activity
iron ion binding
amino acid binding