Hs00852974_cn

• Gene Symbol: CYP1A2
• Assay Reference Genome Location: Chr.15:74749754 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1544
• Gene Name: cytochrome P450 family 1 subfamily A member 2
• Gene Aliases: CP12, P3-450, P450(PA)
• Location: Chr.15:74748843-74756600 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A2	NM_000761.4			NP_000752.2
	AF182274.1			AAF13599.1
	BC067424.1			AAH67424.1
	BC067425.1			AAH67425.1
	BC067426.1			AAH67426.1
	BC067427.1			AAH67427.1
	BC067428.1			AAH67428.1
	BC067429.1			AAH67429.1
	M55053.1			AAA52146.1
	Z00036.1			CAA77335.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	CSK MIR6882 EDC3 MIR4513 SCAMP2 CYP1A2 CPLX3 CYP1A1 LMAN1L ULK3
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	MPI SEMA7A GOLGA6C LOXL1-AS1 LOC729739 SCAMP5 MIR6882 EDC3 PPCDC LOXL1 MIR6881 PML COX5A NEO1 NPTN-IT1 UBL7 CYP1A2 C15orf59-AS1 HCN4 LOC105376731 HIGD2B ULK3 CSK ARID3B ISLR MIR4513 GOLGA6A STRA6 C15orf59 NPTN FAM219B ADPGK LMAN1L ADPGK-AS1 LOC283731 SCAMP2 LOC732265 REC114 CCDC33 LOC107984728 CLK3 CD276 UBL7-AS1 CYP1A1 C15orf39 LOC101929333 ISLR2 RPP25 STOML1 CPLX3 BBS4 CYP11A1 TBC1D21 LOC102723750

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

steroid catabolic process
porphyrin-containing compound metabolic process
xenobiotic metabolic process
toxin biosynthetic process
post-embryonic development
alkaloid metabolic process
regulation of gene expression
monoterpenoid metabolic process
drug metabolic process
dibenzo-p-dioxin metabolic process
epoxygenase P450 pathway
lung development
methylation
response to estradiol
response to lipopolysaccharide
monocarboxylic acid metabolic process
response to immobilization stress
drug catabolic process
exogenous drug catabolic process
cellular respiration
heterocycle metabolic process
hydrogen peroxide biosynthetic process
oxidation-reduction process
oxidative demethylation
cellular response to cadmium ion
oxidative deethylation
omega-hydroxylase P450 pathway

Function(s)

monooxygenase activity
iron ion binding
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
enzyme binding
heme binding
demethylase activity
caffeine oxidase activity
aromatase activity