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Tocris Bioscience™ Tetrabenazine
Potent inhibitor of vesicular monoamine transport
$244.76 - $1030.08
Specifications
| Purity | >98% |
|---|---|
| Product Type | Tetrabenazine |
| Molecular Weight (g/mol) | 317.2 |
| Inhibitors | Tetrabenazine |
Description
Potent inhibitor of vesicular monoamine uptake; depletes stores of dopamine, serotonin and noradrenalin. Binds with high affinity (IC50= 3.2 nM) to vesicular monoamine transporter (VMAT) in chromaffin granule membranes and displays higher affinity for VMAT2 than VMAT1. Also reported to block dopamine receptors. Causes behavioral depression; inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice.Deuterated analog also available.
Specifications
| >98% | |
| Tetrabenazine | |
| 317.2 | |
| Tetrabenazine |
For Research Use Only
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