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Tocris Bioscience™ SB 328437
Potent and selective CCR3 antagonist
Supplier: Tocris Bioscience™ 3650/10
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Description
SB 328437 is a potent and selective CCR3 antagonist (IC50 = 4 nM). Displays > 2500-fold selectivity over C5aR, LTD4, CCR7, CXCR1 and CXCR2 receptors. Inhibits eotaxin-, eotaxin-2- and MCP-4-induced Ca2+ mobilization (IC50 values are 38, 35 and 20 nM respectively) and inhibits eotaxin-, eotaxin-2- and MCP-4-induced eosinophil chemotaxis with similar potencies.Specifications
>99% | |
SB 328437 | |
SB 328437 |
10 mg | |
378.38 |
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