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DL-TBOA, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
DL-TBOA is a competitive, non-transportable blocker of excitatory amino acid transporters (IC50 values are 6 μM, 6 μM and 70 μM, for EAAT2, EAAT3 and EAAT1 respectively). DL-TBOA also inhibits EAAT4 and EAAT5 (Ki values are 4.4 μM and 3.2 μM respectively). DL-TBOA displays high selectivity for EAATs over ionotropic and metabotropic glutamate receptors. DL-TBOA augments SN 38 (Cat. No. 2684) induced colorectal cancer cell death in drug-resistant cell lines. DL-TBOA enhances synaptic activity in the frog labyrinth.
Specifications
Formula Weight | 239.23 |
Percent Purity | >98% |
Quantity | 50 mg |
Chemical Name or Material | DL-TBOA |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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