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  7. Cytochrome C, MP Biomedicals™

Cytochrome C, MP Biomedicals™

Catalog Number MP21014673
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Quantity:
25 mg
100 mg
250 mg
9007-43-6
C40H48FeN6O6S4
892.94
MFCD00130890
UMUOLVQYJUIZKD-RHANTFMNSA-L
cytochrome c, 3-7,12-bis 1-2-amino-3-methylamino-3-oxopropyl sulfanylethyl-18-2-carboxyethyl-3,8,13,17-tetramethylporphyrin-21,23-diid-2-yl propanoic acid; iron 2+
16057918
CC(SC(=O)[C@@H](N)CS)C1=C(C)\C2=C\C3=C(C(C)SC(=O)[C@@H](N)CS)C(C)=C4CC5N=C(\C=C6/N([Fe++]N34)\C(=C/C1=N2)C(C)=C6CCC(O)=O)C(CCC(O)=O)=C5C
9007-43-6
C40H48FeN6O6S4
892.94
MFCD00130890
UMUOLVQYJUIZKD-RHANTFMNSA-L
cytochrome c, 3-7,12-bis 1-2-amino-3-methylamino-3-oxopropyl sulfanylethyl-18-2-carboxyethyl-3,8,13,17-tetramethylporphyrin-21,23-diid-2-yl propanoic acid; iron 2+
16057918
CC(SC(=O)[C@@H](N)CS)C1=C(C)\C2=C\C3=C(C(C)SC(=O)[C@@H](N)CS)C(C)=C4CC5N=C(\C=C6/N([Fe++]N34)\C(=C/C1=N2)C(C)=C6CCC(O)=O)C(CCC(O)=O)=C5C

Description

Regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen. Cytochrome C, MP Biomedicals is an electron-carrying mitochondrial protein that plays a vital role in cellular oxidations i

The transition of Cytochrome C between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter.

  • It has been identified as an important mediator in apoptotic pathways.The release of mitochondrial Cytochrome C into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell.
  • Investigation on the effect of Paris saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through Cytochrome C.
  • The specific sites and extent of oxidation in horse Cytochrome C treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.
Quantity 25 mg
Solubility Information Dark red to Red-Brown Solution at 10mg plus 1mL of water.
IUPAC Name (1Z,6Z,17Z)-15,19-bis(2-carboxyethyl)-4,9-bis[1-(cysteinylsulfanyl)ethyl]-5,10,14,20-tetramethyl-21,23,24,25-tetraaza-22-ferrahexacyclo[9.9.3.1³,⁶.1¹³,¹⁶.0⁸,²³.0¹⁸,²¹]pentacosa-1,3(25),4,6,8,10,14,16(24),17,19-decaene-22,22-bis(ylium)
Formula Weight ∼12,000
Percent Purity ≥90%
Physical Form Powder

Safety and Handling

Recommended Storage −20°C
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