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Chelerythrine chloride, Tocris Bioscience™
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Quantity:
5 mg
Description
Cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 μM) or Bad proteins and stimulates apoptosis.
Specifications
Quantity | 5 mg |
Formula Weight | 383.83 |
Percent Purity | >98% |
Chemical Name or Material | Chelerythrine chloride |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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