Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Facility Safety and Maintenance
  4. Cleaning Supplies and Equipment
  5. Cleaners and Disinfectants
  6. Laboratory Surfactants and Wetting Agents
  7. CHAPS, Electrophoresis Grade, Thermo Scientific Chemicals

CHAPS, Electrophoresis Grade, Thermo Scientific Chemicals

Catalog Number AAJ6735914
Click to view available options
Quantity:
5 g
10 g
25 g
75621-03-3
C32H58N2O7S
614.883
MFCD00012116
UMCMPZBLKLEWAF-GBSSQDIOSA-N
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
134129639
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
75621-03-3
C32H58N2O7S
614.883
MFCD00012116
UMCMPZBLKLEWAF-GBSSQDIOSA-N
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
134129639
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

Description

CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, CAS # 75621-03-3, is a non-denaturing zwitterionic detergent that can be used for solubilizing membrane proteins.

CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• CHAPS (3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate) is a zwitterionic non-denaturing detergent
• It is suitable for applications which require protection of native protein conformation
Applications
• CHAPS can be used for the solubilization and purification of membrane proteins
• It is also used in conjunction with nonionic detergents like Triton X-100
• It can be used as a non-denaturing zwitterionic detergent for the study of membrane chemistry

TRUSTED_SUSTAINABILITY
Color White
Physical Form Powder
Melting Point 156°C to 158°C
Quantity 25 g
Solubility Information Soluble in water (10mg/ml). Soluble in DMF and hot methanol.
Formula Weight 614.88
Grade Electrophoresis
Chemical Name or Material CHAPS

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Ambient temperatures; Store under Nitrogen
SDS

RUO – Research Use Only

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit