Histology Workflow Products


   Bringing Hospital Lab Expertise to Your Clinic


Bringing Hospital Lab Expertise to Your Clinic

Collect, Process, and Prepare

Histology, a key component of anatomic pathology (AP), is key to tissue-based diagnoses and successful patient treatment.

Once an essentially manual process, automation is being introduced to the histology lab. Additionally, the histologist may now perform molecular diagnostics on tissue samples, and digital microscopy makes it easier and faster to share critical information with other clinicians.

Histology Workflow

A typical histology workflow consists of:

  • Specimen Collection: tissue specimens delivered from the operating room or physician office are examined, dissected, and placed into labeled cassettes 
  • Tissue Processing: the cassettes are placed into a processor that dehydrates, clears, and infiltrates the tissue (process takes 10 to 12 hours)
  • Tissue Preparation: the tissue is encased in paraffin or other media, sliced using a microtome, placed on microscope slides, stained, and coverslipped 

Multiple slides from each sample are assembled as a “case” and forwarded to a pathologist for microscopic examination and evaluation.

Specimen Collection

During grossing, the pathologist measures, describes, and dissects the specimen and places pieces of the tissue into labeled plastic cassettes (blocks). Because the tissue may have been placed in formaldehyde or other tissue preservatives, working under a hood or enclosure is recommended.


Grossing Station

Protect users from formaldehyde and other chemical exposure during grossing.


Cassette Label Printer

Manual or automated cassette labeling is key to proper specimen identification and tracking.



Process “frozen sections” quickly with cryotomes that combine a microtome-like cutting mechanism with a freezer unit.


Storage Systems

Safely store and save time sorting, archiving, and retrieving your slides and tissue blocks.

Tissue Processing

The tissue processing step is performed with specific equipment and a series of solvents and other chemicals. Processing may produce odors or require special ventilation like an exhaust or canopy hood.


Tissue Processors

Automate the overnight process of subjecting tissue to a series of alcohol solutions, xylene clearing agents, and paraffin.

Tissue Preparation

Tissue preparation includes embedding, sectioning, staining, and coverslipping. The specimen is embedded in paraffin, the blocks are sliced using microtomes, and the tissue sections are placed onto glass microscopic slides. The slides are stained and then coverslipped to create a permanent preparation.


Tissue Embedding Station

Embedding stations facilitate the embedding process with cooling surfaces that rapidly harden paraffin.



Section tissues with manual, rotary, sliding, or automatic microtomes with reusable or disposable blades.


Slides and Slide Labeling

The right type of slide and accurate, reliable labeling are key to successful specimen mounting and identification.



Choose reagents and antibodies to help identify cellular antigens and markers of specific tissue and tumor types.



Coverslips and mounting media make your tissue slides a part of the patient’s permanent record. Automated coverslippers help to eliminate tedious and labor-intensive steps.