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MilliporeSigma™ YUMM1.7 D4 Mouse Melanoma Cell Line
YUMM1.7D4 melanoma cell line is a diploid clone of YUMM1.7, developed as immunicompetent cell line
Supplier: MilliporeSigma™ SCC227
Description
- Immunocompetent cell line that recapitulates genetic drivers found in a significant proportion of human melanomas
- Diploid genotype of YUMM1.7D4 cells greatly enhances efficiency of CRISPR-based screens with higher frequency of biallelic knockout compared to tetraploid cells
- Syngeneic with the immunocompetent C57/B1/6 mouse background, retaining genetic markers of the Braf/Pten mouse model in which melanoma tumors develop with short latency
Specifications
Store in liquid nitrogen, Cells can be cultured 10 passages after initial thawing without significantly affecting cell marker expression and functionality | |
Cancer Cells | |
Cell Culture | |
≥ 1 x 106 Cells/Vial |
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