Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Furopyridines
  7. PI 103 hydrochloride, Tocris Bioscience™

PI 103 hydrochloride, Tocris Bioscience™

Catalog Number 293050
Click to view available options
Quantity:
1 mg
10 mg
50 mg
This item is not returnable. View return policy
371935-79-4
C19H17ClN4O3
384.82
XSQMYBFFYPTMFE-UHFFFAOYSA-N
pi 103 hydrochloride, pi-103 hydrochloride, pi103 hydrochloride, pubchem22442, pi-103, hydrochloride, c19h16n4o3.clh, pi 103 hydrochloride;pi103 hydrochloride, 3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride, 3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
16739368
3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
This item is not returnable. View return policy
371935-79-4
C19H17ClN4O3
384.82
XSQMYBFFYPTMFE-UHFFFAOYSA-N
pi 103 hydrochloride, pi-103 hydrochloride, pi103 hydrochloride, pubchem22442, pi-103, hydrochloride, c19h16n4o3.clh, pi 103 hydrochloride;pi103 hydrochloride, 3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride, 3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
16739368
3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl

Description

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.
Quantity 50 mg
Formula Weight 384.82
Percent Purity >98%
Chemical Name or Material PI 103 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit