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PF 915275, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10 μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. Orally active.
Specifications
Quantity | 50 mg |
Formula Weight | 350.39 |
Percent Purity | >98% |
Chemical Name or Material | PF 915275 |
Safety and Handling
Recommended Storage | Store at Room Temperature |
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