Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Biphenyls and derivatives
  8. PF 915275, Tocris Bioscience™

PF 915275, Tocris Bioscience™

Catalog Number 329150
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
857290-04-1
C18H14N4O2S
350.396
ZESFDAKNYJQYKO-UHFFFAOYSA-N
n-6-aminopyridin-2-yl-4'-cyanobiphenyl-4-sulfonamide, n-6-aminopyridin-2-yl-4'-cyano-1,1'-biphenyl-4-sulfonamide, d07fhw, n-pyridin-2-yl arylsulfonamide, 26, n-6-aminopyridin-2-yl 4'-cyanobiphenyl-4-sulfonamide, n-6-amino-2-pyridinyl-4'-cyano-1,1'-biphenyl-4-sulfonamide, 1,1'-biphenyl-4-sulfonamide, n-6-amino-2-pyridinyl-4'-cyano, n-6-amino-pyridin-2-yl-4'-cyano-1,1'-biphenyl-4-sulfonamide
23725123
N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide
C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N
This item is not returnable. View return policy
857290-04-1
C18H14N4O2S
350.396
ZESFDAKNYJQYKO-UHFFFAOYSA-N
n-6-aminopyridin-2-yl-4'-cyanobiphenyl-4-sulfonamide, n-6-aminopyridin-2-yl-4'-cyano-1,1'-biphenyl-4-sulfonamide, d07fhw, n-pyridin-2-yl arylsulfonamide, 26, n-6-aminopyridin-2-yl 4'-cyanobiphenyl-4-sulfonamide, n-6-amino-2-pyridinyl-4'-cyano-1,1'-biphenyl-4-sulfonamide, 1,1'-biphenyl-4-sulfonamide, n-6-amino-2-pyridinyl-4'-cyano, n-6-amino-pyridin-2-yl-4'-cyano-1,1'-biphenyl-4-sulfonamide
23725123
N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide
C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N

Description

Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor

Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10 μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. Orally active.
Quantity 50 mg
Formula Weight 350.39
Percent Purity >98%
Chemical Name or Material PF 915275

Safety and Handling

Recommended Storage Store at Room Temperature
Provide Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit