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  8. LY 487379 hydrochloride, Tocris Bioscience™

LY 487379 hydrochloride, Tocris Bioscience™

Catalog No. 328350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective positive allosteric modulator of mGlu2 receptors

Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors. Promotes cognitive flexibility in a rat model.

Chemical Identifiers

CAS 353229-59-1
Molecular Formula C21H20ClF3N2O4S
Molecular Weight (g/mol) 488.906
InChI Key LPWFRDWTOKLHJC-UHFFFAOYSA-N
Synonym ly 487379 hydrochloride, ly-487379 hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-3-pyridinylmethyl ethanesulfonamide hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-ylmethyl ethanesulfonamide hydrochloride, ly-487379 hydrochloride hplc, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-yl methyl ethane-1-sulfonamide-hydrogen chloride 1/1, n-4-2-methoxyphenoxy phenyl-n-2,2,2-trifluoroethylsulfonyl pyrid-3-ylmethylamine hydrochloride
PubChem CID 56972206
IUPAC Name 2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide;hydrochloride
SMILES COC1=CC=CC=C1OC2=CC=C(C=C2)N(CC3=CN=CC=C3)S(=O)(=O)CC(F)(F)F.Cl

Specifications

Quantity 50 mg
Formula Weight 488.91
Percent Purity >99%
Chemical Name or Material LY 487379 hydrochloride

Safety and Handling

Recommended Storage Store at -20°C
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