Invitrogen™ Human Osteopontin Synthetic Peptide

Synthetic Peptide

Supplier:  Invitrogen™ PEP1622

Catalog No. PEP1622

Description

SPP1 Synthetic Peptide, PEP-1622, from Invitrogen.

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D. This peptide corresponds to 18 amino acids near the amino terminus of SPP1.PEP-1622 can be used as a blocking peptide with polyclonal antibody PA5-34579. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

Specifications

• Gene ID (Entrez): 6696
• Purification Method: purified
• Common Name: Human Osteopontin
• Content And Storage: -20°C
• Format: Liquid
• For Use With (Application): Blocking Assay, Control
• Lyophilized: No
• Product Type: Peptide
• Regulatory Status: RUO - research use only

• Species: Human
• Accession Number: P10451
• Concentration: 200 μg/mL
• Description: Synthetic Peptide
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• Gene Symbol: SPP1
• Preservative: 0.02% sodium azide
• Quantity: 50 μg
• Storage Buffer: PBS