STEMCELL Technologies Human Recombinant SCF, Size: 10 µg
Supplier: STEMCELL Technologies 78062.1
Use stem cell factor (SCF) to promote cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. SCF is an early-acting cytokine that activates PI3K, JAK/STAT, and MAPK pathways upon binding to its receptor. Together with other cytokines like thrombopoietin and Flt3/Flk-2 Ligand, SCF is used to promote expansion of primitive hematopoietic stem cells and multipotent progenitor cells in culture (Martin et al. Cell, 1990; Kent et al. Clin Cancer Res, 2008.). In combination with various growth factors and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy VC. Blood, 1997). Human recombinant SCF from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 15 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: Kit ligand, Mast cell growth factor, Steel factor, Stem cell factor.
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