Cytiva HiTrap™ Capto™ Core 700 Columns

HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess medium for intermediate purification and polishing of viruses and other large biomolecules.

Supplier:  Cytiva 17548151

Catalog No. 45-002-598

Description

Capto Core 700 is a novel, layered bead chromatography medium consisting of a porous outer layer and ligand-activated core.

• High capacity and productivity in flowthrough mode.
• Wide operational window of pH and conductivity.
• Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
• The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged.
• These internalized ligands bind impurities strongly over a wide range of pH and salt concentration.
• The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

Specifications

• Buffer: 1M NaOH, 6M Guanidine Hydrochloride, 30% Isopropanol and 70% Ethanol
• Bed Volume: 1mL
• Diameter (Metric) Inner: 7mm
• Flow Rate: <500cm/hr.
• Ligand Type: Octylamine
• pH Range: 2 to 14
• Support Type: Highly Cross-linked Agarose
• Column Type: Multimodal Column

• Product Type: HiTrap Capto Core 700 multimodal column
• Diameter (English) Inner: 0.27 in.
• Quantity: 5 x 1mL
• Material: Polypropylene
• Max. Pressure: 5 bar
• Particle Size: 90μm
• Content And Storage: 4° to 30°C
• For Use With (Application): Intermediate purification and polishing of viruses and other large biomolecules