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Cytiva HiScreen™ Capto™ adhere Multimodal Prepacked Column
For intermediate purification and polishing of monoclonal antibodies after the protein A capture step
Supplier: Cytiva 28926981
Description
- Strong multimodal anion exchanger with N-benzyl-n-methyl ethanolamine ligand
- Offers alternative selectivity compared to traditional anion exchangers
- In flowthrough mode, removal of leached protein A, aggregates, host cell proteins, nucleic acids and viruses from MAbs is performed
- Antibodies pass directly through the column while the contaminants remain bound
- Highly cross-linked agarose matrix
- Ready-to-use columns for convenient process development optimization
- Bed height of 10cm is designed to allow method optimization and parameter screening
- Easily connected in series to achieve 20cm bed height
Specifications
| 1M Acetic Acid, 1M NaOH | |
| 4.7mL | |
| 7.7mm | |
| 3.93 in. | |
| <600cm/hr. | |
| N-benzyl-n-methyl Ethanolamine | |
| 3 to 12 | |
| Highly Cross-linked Agarose | |
| Multimodal Column |
| HiScreen Capto adhere column | |
| 0.3 in. | |
| 1 x 4.7mL | |
| 100mm | |
| Polypropylene | |
| 3 bar | |
| 75μm | |
| 4° to 30°C | |
| Optimization and parameter screening |
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