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Genistein, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Genistein is a phytoestrogen with a wide range of biological actions. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase, binds to PPARγ and estrogen receptors and acts as an agonist at GPER. Genistein inhibits aggregation and fibrilization of Aβ42 and amylin37 (hiAPP). In Huntington's disease fibroblast cells, Genistein reduces intracellular mutant huntingtin (mHTT) aggregates and induces degradation of mHTT; in a cellular model of Huntington's disease, Genistein corrects the mutant phenotype through stimulation of autophagy.
Specifications
Quantity | 50 mg |
Formula Weight | 270.24 |
Percent Purity | >98% |
Chemical Name or Material | Genistein |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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