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Tocris Bioscience™ CRID3 sodium salt
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
$294.64 - $1229.60
Specifications
| Purity | 98% |
|---|---|
| Description | CRID3 sodium salt |
| Molecular Weight (g/mol) | 426.46 |
| Product Type | CRID3 sodium salt |
Description
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production. Selective for NLRP3 inflammasome over NLRC4 inflammasome and Toll-like receptor signaling. Inhibits inflammasome activation by soluble and crystalline NLRP3 stimuli. Reduces severity of experimental autoimmune encephalomyelitis, skin inflammation and airway inflammation in mice. Also glutathione S-transferase omega 1 inhibitor. Orally bioavailable.Specifications
| 98% | |
| CRID3 sodium salt | |
| 426.46 | |
| CRID3 sodium salt |
For Research Use Only
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