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  7. Compound 401, Tocris Bioscience™

Compound 401, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
168425-64-7
C16H15N3O2
281.315
BVRDQVRQVGRNHG-UHFFFAOYSA-N
compound 401, 2-morpholino-4h-pyrimido 2,1-a isoquinolin-4-one, 2-morpholin-4-yl pyrimido 2,1-a isoquinolin-4-one, 2-morpholin-4-yl-pyrimido 2,1-a isoquinolin-4-one, 2-4-morpholinyl-4h-pyrimido 2,1-a isoquinolin-4-one, compound401, d0t0by, 2-morpholin-1-yl pyrimido 2,1-a isoquinolin-4-one
10039361
2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-one
C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2
This item is not returnable. View return policy
168425-64-7
C16H15N3O2
281.315
BVRDQVRQVGRNHG-UHFFFAOYSA-N
compound 401, 2-morpholino-4h-pyrimido 2,1-a isoquinolin-4-one, 2-morpholin-4-yl pyrimido 2,1-a isoquinolin-4-one, 2-morpholin-4-yl-pyrimido 2,1-a isoquinolin-4-one, 2-4-morpholinyl-4h-pyrimido 2,1-a isoquinolin-4-one, compound401, d0t0by, 2-morpholin-1-yl pyrimido 2,1-a isoquinolin-4-one
10039361
2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-one
C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2

Description

Selective DNA-PK and mTOR inhibitor

Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC50 values are 0.28 and 5.3 μM respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC50 values are all > 100 μM). Induces apoptosis in vitro.
Quantity 50 mg
Formula Weight 281.31
Percent Purity >99%
Chemical Name or Material Compound 401

Safety and Handling

Recommended Storage : Store at Room Temperature

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