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BD AbSeq™ CD64 Mouse, anti-Human, Oligo, Clone: 10.1, BD AbSeq™
Mouse Monoclonal Antibody
Supplier: BD AbSeq™ 940023
Description
The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
Specifications
CD64 | |
10.1 | |
Mouse | |
RUO | |
Human |
Single Cell 3' Sequencing | |
Oligo | |
25 Tests | |
Primary |
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