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  7. A 769662, Tocris Bioscience™

A 769662, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
844499-71-4
C20H12N2O3S
360.387
CTESJDQKVOEUOY-UHFFFAOYSA-N
4-hydroxy-3-2'-hydroxy-1,1'-biphenyl-4-yl-6-oxo-6,7-dihydrothieno 2,3-b pyridine-5-carbonitrile, unii-p68477cd2c, 6,7-dihydro-4-hydroxy-3-2'-hydroxy 1,1'-biphenyl-4-yl-6-oxo-thieno 2,3-b pyridine-5-carbonitrile, 4-hydroxy-3-2'-hydroxybiphenyl-4-yl-6-oxo-6,7-dihydrothieno 2,3-b pyridine-5-carbonitrile, 4-hydroxy-3-4-2-hydroxyphenyl phenyl-6-oxo-7h-thieno 2,3-b pyridine-5-carbonitrile, thieno 2,3-b pyridine-5-carbonitrile, 6,7-dihydro-4-hydroxy-3-2'-hydroxy 1,1'-biphenyl-4-yl-6-oxo, 4cff, 4-hydroxy-3-2'-hydroxy-1,1'-biphenyl-4-yl-6-oxo-7h-thieno 2,3-b pyridine-5-carbonitrile
54708532
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile
C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CSC4=C3C(=C(C(=O)N4)C#N)O)O
This item is not returnable. View return policy
844499-71-4
C20H12N2O3S
360.387
CTESJDQKVOEUOY-UHFFFAOYSA-N
4-hydroxy-3-2'-hydroxy-1,1'-biphenyl-4-yl-6-oxo-6,7-dihydrothieno 2,3-b pyridine-5-carbonitrile, unii-p68477cd2c, 6,7-dihydro-4-hydroxy-3-2'-hydroxy 1,1'-biphenyl-4-yl-6-oxo-thieno 2,3-b pyridine-5-carbonitrile, 4-hydroxy-3-2'-hydroxybiphenyl-4-yl-6-oxo-6,7-dihydrothieno 2,3-b pyridine-5-carbonitrile, 4-hydroxy-3-4-2-hydroxyphenyl phenyl-6-oxo-7h-thieno 2,3-b pyridine-5-carbonitrile, thieno 2,3-b pyridine-5-carbonitrile, 6,7-dihydro-4-hydroxy-3-2'-hydroxy 1,1'-biphenyl-4-yl-6-oxo, 4cff, 4-hydroxy-3-2'-hydroxy-1,1'-biphenyl-4-yl-6-oxo-7h-thieno 2,3-b pyridine-5-carbonitrile
54708532
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile
C1=CC=C(C(=C1)C2=CC=C(C=C2)C3=CSC4=C3C(=C(C(=O)N4)C#N)O)O

Description

Potent AMPK activator

Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo. Also inhibits proliferation of mesenchymal stem cells, and impedes reprogramming of mouse embryonic fibroblasts to iPSCs. Activates autophagy.
Quantity 50 mg
Formula Weight 360.39
Percent Purity >98%
Chemical Name or Material A 769662

Safety and Handling

Recommended Storage : Store at +4°C