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  7. 4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals

4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals

Catalog Number AAB2287714
Click to view available options
Quantity:
1 g
5 g
25 g
486-66-8
C15H10O4
254.241
MFCD00016954
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
5281708
CHEBI:28197
7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
486-66-8
C15H10O4
254.241
MFCD00016954
ZQSIJRDFPHDXIC-UHFFFAOYSA-N
daidzein, 4',7-dihydroxyisoflavone, daidzeol, 7,4'-dihydroxyisoflavone, 7-hydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, diadzein, 7-hydroxy-3-4-hydroxyphenyl-4h-1-benzopyran-4-one, 4h-1-benzopyran-4-one, 7-hydroxy-3-4-hydroxyphenyl, 7-hydroxy-3-4-hydroxyphenyl chromen-4-one, 7-hydroxy-3-4-hydroxyphenyl-4-benzopyrone
5281708
CHEBI:28197
7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O

Description

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
TRUSTED_SUSTAINABILITY
Melting Point 328°C to 332°C (decomposition)
Quantity 25 g
Beilstein 231523
Merck Index 14,2801
Solubility Information Insoluble in water. Soluble in DMSO (25mg/ml),ethanol (2mg/ml),DMF (10mg/ml),and 1:10 DMSO:PBS (pH 7.2) (0.15mg/ml).
Formula Weight 254.24
Percent Purity 97%
Chemical Name or Material 4',7-Dihydroxyisoflavone

Safety and Handling

Hazard Category H315-H319
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
EINECSNumber 207-635-4
RTECSNumber DJ3100040
TSCA No
SDS

RUO – Research Use Only

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