Hs06639183_cn

• Gene Symbol: OGG1
• Assay Reference Genome Location: Chr.3:9770911 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 4968
• Gene Name: 8-oxoguanine DNA glycosylase
• Gene Aliases: HMMH, HOGG1, MUTM, OGH1
• Location: Chr.3:9749944-9788246 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OGG1	XM_011533760.1			XP_011532062.1
	XM_017006494.1			XP_016861983.1
	XM_017006496.1			XP_016861985.1
	XM_017006497.1			XP_016861986.1
	XM_017006499.1			XP_016861988.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1010768	Chr.3:9502870 - 9873902 on Build GRCh38	Gain	MTMR14 TADA3 CAMK1 ARPC4 ARPC4-TTLL3 LOC107986062 LHFPL4 CIDEC BRPF1 RPUSD3 TTLL3 OGG1 CPNE9

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

acute inflammatory response
base-excision repair
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
response to oxidative stress
aging
response to radiation
response to light stimulus
response to estradiol
regulation of protein import into nucleus, translocation
nucleotide-excision repair, DNA incision
response to drug
negative regulation of apoptotic process
depurination
depyrimidination
response to ethanol
response to folic acid
cellular response to cadmium ion
negative regulation of double-strand break repair via single-strand annealing

Function(s)

damaged DNA binding
endonuclease activity
protein binding
microtubule binding
oxidized purine nucleobase lesion DNA N-glycosylase activity
oxidized purine DNA binding
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity