Hs06553459_cn

• Gene Symbol: KMO
• Assay Reference Genome Location: Chr.1:241538770 on build GRCh38
• Cytoband: 1q43

Target Gene Details

• Entrez Gene ID: 8564
• Gene Name: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
• Gene Aliases: dJ317G22.1
• Location: Chr.1:241531883-241595647 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KMO	NM_003679.4			NP_003670.2
	XM_005273337.1			XP_005273394.1
	XM_005273338.3			XP_005273395.1
	XM_017002649.1			XP_016858138.1
	AF056032.1			AAC62615.1
	AK291558.1
	AK310937.1
	AU137977.1
	BC005297.1			AAH05297.1
	BP276365.1
	Y13153.1			CAA73613.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv549460	Chr.1:241331278 - 241669985 on Build GRCh38	Gain	FH WDR64 KMO RGS7 CHML OPN3
nsv1002214	Chr.1:241295639 - 241936488 on Build GRCh38	Gain	FH WDR64 KMO RGS7 EXO1 CHML OPN3

More Information

Additional Information:

For this assay, SNP(s) [rs67267325] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

tryptophan catabolic process
response to salt stress
tryptophan catabolic process to kynurenine
NAD metabolic process
quinolinate biosynthetic process
'de novo' NAD biosynthetic process from tryptophan
anthranilate metabolic process
secondary metabolite biosynthetic process
oxidation-reduction process
kynurenine metabolic process

Function(s)

kynurenine 3-monooxygenase activity
NAD(P)H oxidase activity
flavin adenine dinucleotide binding
FAD binding