Hs02635168_cn

• Gene Symbol: ESCO2
• Assay Reference Genome Location: Chr.8:27780232 on build GRCh38
• Cytoband: 8p21.1

Target Gene Details

• Entrez Gene ID: 157570
• Gene Name: establishment of sister chromatid cohesion N-acetyltransferase 2
• Gene Aliases: 2410004I17Rik, EFO2, RBS
• Location: Chr.8:27771949-27812404 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ESCO2	NM_001017420.2			NP_001017420.1
	XM_011544421.2			XP_011542723.1
	XM_011544422.2			XP_011542724.1
	AF306679.1
	AK124215.1
	AL832666.1
	AY882862.1			AAX68677.1
	BC034641.1			AAH34641.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv524133	Chr.8:27776547 - 27858791 on Build GRCh38	Loss	ESCO2 PBK
nsv519636	Chr.8:27778100 - 27831788 on Build GRCh38	Gain	ESCO2 PBK
nsv1017032	Chr.8:27767011 - 27821659 on Build GRCh38	Loss	ESCO2 PBK CCDC25

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acetyltransferase

Gene Ontology Categories:

Process(es)

hematopoietic progenitor cell differentiation
regulation of DNA replication
double-strand break repair
cell cycle
chromosome segregation
post-translational protein acetylation
protein localization to chromatin

Function(s)

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
N-acetyltransferase activity
metal ion binding