Hs02146347_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137426263 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	AB095031.1			BAC76710.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	ENTPD8 EXD3 NOXA1
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	ENTPD8 NSMF PNPLA7 EXD3 MIR7114 NOXA1
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	ENTPD8 EXD3 NOXA1
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 EXD3 NOXA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	SLC34A3 FBXW5 C8G PTGDS TUBB4B NOXA1 SSNA1 NDOR1 TOR4A CCDC183-AS1 UAP1L1 CCDC183 MIR4292 PHPT1 LRRC26 MIR4479 STPG3 MAN1B1-AS1 C9orf173-AS1 NPDC1 NSMF CLIC3 NELFB TMEM210 TMEM203 EDF1 LOC101930307 NRARP LCNL1 C9orf172 MAMDC4 CYSRT1 PRR31 FAM166A MIR3621 DPP7 C9orf139 ENTPD8 RABL6 MAN1B1 PNPLA7 TPRN FUT7 LCN12 SAPCD2 MIR7114 RNF208 RNF224 TRAF2 EXD3 ENTPD2 C9orf142 ANAPC2 GRIN1 ABCA2
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	SLC34A3 RNF208 RNF224 CYSRT1 EXD3 FAM166A MIR3621 LRRC26 TUBB4B STPG3 C9orf173-AS1 NOXA1 ENTPD8 SSNA1 TPRN NELFB TMEM210 TMEM203 NDOR1 ANAPC2 GRIN1 NRARP TOR4A

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding