Hs01756189_cn

• Gene Symbol: HES3
• Assay Reference Genome Location: Chr.1:6245552 on build GRCh38
• Cytoband: 1p36.31

Target Gene Details

• Entrez Gene ID: 390992
• Gene Name: hes family bHLH transcription factor 3
• Gene Aliases: bHLHb43
• Location: Chr.1:6244192-6245578 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HES3	NM_001024598.3			NP_001019769.1
	CX755241.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8n67	Chr.1:6220621 - 6264303 on Build GRCh38	Gain	RNF207 LINC00337 ACOT7 GPR153 ICMT HES3
nsv831425	Chr.1:6129291 - 6264418 on Build GRCh38	Loss	RNF207 LINC00337 CHD5 ACOT7 RPL22 GPR153 ICMT LOC102724450 HES3
nsv545236	Chr.1:6161915 - 6262876 on Build GRCh38	Loss	RNF207 LINC00337 CHD5 RPL22 GPR153 ICMT LOC102724450 HES3
nsv545237	Chr.1:6240990 - 6250176 on Build GRCh38	Loss	GPR153 HES3
nsv508825	Chr.1:6221275 - 6286549 on Build GRCh38	Insertion	RNF207 LINC00337 ACOT7 GPR153 ICMT HES3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
midbrain-hindbrain boundary morphogenesis
oculomotor nerve development
trochlear nerve development
hindbrain morphogenesis
midbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of neuron differentiation

Function(s)

DNA binding
transcription factor binding
protein dimerization activity