Hs01151385_cn

• Gene Symbol: ZNF281
• Assay Reference Genome Location: Chr.1:200410018 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 23528
• Gene Name: zinc finger protein 281
• Gene Aliases: ZBP-99, ZNP-99
• Location: Chr.1:200404947-200483604 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF281	NM_001281293.1			NP_001268222.1
	NM_001281294.1			NP_001268223.1
	NM_012482.4			NP_036614.1
	XM_017000887.1	4	1422	XP_016856376.1
	XM_017000888.1	4	380	XP_016856377.1
	AJ132592.1			CAB70968.1
	AK027284.1
	AK094701.1
	BC060820.1			AAH60820.1
	BP216938.1
	DB150929.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv548990	Chr.1:200400630 - 200452338 on Build GRCh38	Loss	ZNF281

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
embryonic body morphogenesis
negative regulation of gene expression
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
stem cell differentiation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding