Hs00713290_cn

• Gene Symbol: DDX6
• Assay Reference Genome Location: Chr.11:118751392 on build GRCh38
• Cytoband: 11q23.3

Target Gene Details

• Entrez Gene ID: 1656
• Gene Name: DEAD-box helicase 6
• Gene Aliases: HLR2, P54, RCK
• Location: Chr.11:118747763-118791263 on Build GRCh38
• Assay Gene Location: Within Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DDX6	NM_001257191.2	14	2526	NP_001244120.1
	NM_004397.5	14	2598	NP_004388.2
	XM_005271417.3	14	2543	XP_005271474.1
	XM_011542644.1	13	2469	XP_011540946.1
	XM_011542645.1	13	2451	XP_011540947.1
	XM_017017251.1	13	2414	XP_016872740.1
	AK093657.1
	BC039826.1	7	1378	AAH39826.1
	BC065007.1			AAH65007.1
	D17532.1	14	2471	BAA04482.1
	Z11685.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832283	Chr.11:118566790 - 118786484 on Build GRCh38	Loss	TREH PHLDB1 ARCN1 IFT46 DDX6 MIR6716
esv2762946	Chr.11:118714898 - 118762551 on Build GRCh38	Gain	DDX6

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

regulation of translation
RNA secondary structure unwinding
viral RNA genome packaging
stem cell population maintenance
cytoplasmic mRNA processing body assembly
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
negative regulation of neuron differentiation
cell-cell adhesion

Function(s)

RNA helicase activity
ATP-dependent RNA helicase activity
helicase activity
protein binding
ATP binding
protein domain specific binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion