ACTA1, ACTA2, ACTB, ACTG1, ACTG2, ADCY1, ADCY2, ADCY3, ADCY4, ADCY5, ADCY6, ADCY7, ADCY8, ADCY9, AK1, AK2, AK3, AK5, AK7, ARF1, ARF3, ARF4, ARF5, ARF6, CFTR, CLCA1, CLCA2, CLCA4, CLCN1, CLCN2, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, CLIC1, CLIC2, CLIC4, CLIC5, CLNS1A, CNGA1, CNGA3, CNGB1, CNGB3, ERO1L, GNAS, HSPG2, KCNK1, K...CNK2, KCNK3, KCNK4, KCNK9, PDIA4, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, PLCD4, PLCG1, PLCG2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCH, PRKCI, PRKCQ, PRKCZ, PRKD1, PRKD3, SCN10A, SCN1A, SCN1B, SCN2A, SCN2B, SCN3A, SCN3B, SCN4A, SCN5A, SCN8A, SCN9A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, SEC61A1, SEC61A2, SEC61B, SEC61G
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Cholera is one of the most severe diarrheal diseases that affect humans and is responsible for significant morbidity and mortality especially among children in developing countries. It is characterized by numerous, voluminous watery stools, often accompan ...ied by vomiting, and resulting in hypovolemic shock and acidosis. It is caused by certain members of the species Vibrio cholerae which can also cause mild or inapparent infections. Other members of the species may occasionally cause isolated outbreaks of milder Diarrhea whereas others the vast majorities are free-living and not associated with disease. The causative agent of Cholera, Vibrio cholerae, is a Gram-negative highly motile bacterium with a single polar flagellum that inhabits rivers, estuaries or other aquatic environments. Cholera is a water-borne disease and the bacteria are usually transmitted via contaminated food or water. Upon ingestion, the organisms colonize the small intestine where they elaborate the potent CTx (Cholera Toxin) that is directly responsible for the profuse diarrhea characteristic of the disease. The V. cholerae bacteria are shed in large numbers in the typical ''rice water'' stool into the environment, where they can associate with other members of the ecosystem until they are ingested again, thus completing the life cycle of this organism.
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